湖南大湘西地区城市经济竞争力比较研究

在现有城市经济竞争力分析的国内外研究成果的基础上,依据城市竞争力相关理论,借鉴国内外评价机构的评价模型和分析体系,构建出湖南省大湘西地区城市经济竞争力的评价指标体系,并利用因子分析法对大湘西地区城市经济竞争力进行综合评价,并对各个城市的经济竞争力进行比较研究.在此基础上,有针对性地提出了促进大湘西地区城市经济竞争力提升的对策建议.     

中国战略性新兴产业国际竞争力评价

以"新钻石模型"为基础,从产业环境、产业支撑和产业创新等3个维度构建战略性新兴产业国际竞争力评价指标体系.运用2005~2014年的面板数据对战略性新兴产业进行因子分析.评价结果显示,电子及通信设备制造业与医药制造业国际竞争力明显高于计算机及办公设备制造业与医疗仪器设备及仪器仪表制造业.航空航天器及设备制造业国际竞争力有很大提升潜力.电子及通信设备制造业创新能力表现突出,但战略性新兴产业整体创新能力较低.     

统计模型在中文文本挖掘中的应用

本文讨论了中文文本挖掘的三个问题:分词、关键词提取和文本分类。对分词问题,介绍了基于层叠隐马尔可夫模型的ICTCLAS分词法,以及将词与词之间的分隔视为缺失数据并用EM算法求解的WDM方法;对关键词提取问题,提出了贝叶斯因子法,并介绍了使用稀疏回归的CCS方法;对文本分类问题,介绍了根据关键词频率建立分类器的方法,以及先建立主题模型再根据主题概率建立分类器的方法。本文通过两组文本数据对上述方法进行比较,并给出使用建议。     

Electron localization function from density components

This work addresses the decomposition of the Electron Localization Function (ELF) into partial density contributions using an appealing split of kinetic energy densities. Regarding the degree of the electron localization, the relationship between ELF and its usual spin‐polarized formula is discussed. A new polarized ELF formula, built from any subsystems of the density, and a localization function, quantifying the measure of electron localization for only a subpart of the total system are introduced. The methodology appears tailored to describe the electron localization in bonding patterns of subsystems, such as the local nucleophilic character. Beyond these striking examples, this work opens up opportunities to describe any electronic properties that depend only on subparts of the density in atoms, molecules, or solids. © 2016 Wiley Periodicals, Inc.     

Removal of uranium (VI) from nuclear effluents onto aluminophosphate and silicoaluminophosphate molecular sieves

Aluminophosphate and silicoaluminophosphate molecular sieves with both five (AFI) and eleven (AEL) type structures are synthesized by hydrothermal crystallization at 473 K, using tripropylamine and dipropylamine as a structure-directing template. The as-prepared AFI and AEL sieves are characterized and then assessed as sorbents for uranium (VI) from radioactive effluents. The sorption process is used to reduce the volumes of effluents and convert them into a stable solid waste. The batch experimental studies are carried out to evaluate the AEL and AFI structure effect on the removal of uranium. The AlPO₄-5, SAPO-5, AlPO₄-11 and SAPO-11 are applied to radioactive effluents with different activities obtained from Nuclear Research Center of Draria, Algeria. Important decontamination factor values are obtained for AFI sorbents. Thermodynamic parameters, namely, the enthalpy (ΔH), entropy (ΔS) and free energy (ΔG) for each sorption process are calculated. The collected results indicated that sorbents are effective materials for the removal of uranium (VI) ions, the sorbent with AFI structure being a highly effective material for the removal of uranium (VI) ions from nuclear effluents.     

Direct analysis of free amino acids by mixed‐mode chromatography with tandem mass spectrometry

We developed a straightforward, robust, and relatively fast method for the analysis of amino acids by mixed‐mode high‐performance liquid chromatography coupled to electrospray ionization tandem mass spectrometry. The method does not involve derivatization and allows the detection of 21 amino acids, representing a wide range of isoelectric points, in less than 40 min. Chromatographic separation was governed by a silica‐based mixed‐mode column providing simultaneous hydrophobic and ion exchange separation mechanisms. The use of tandem mass spectrometry increased selectivity, reducing potential problems associated with poor selectivity in the chromatographic system. For an injection volume of 1 μL, we obtained detection limits <3 μM for the majority of analytes. For all analytes, a linearity of r > 0.99 was obtained, recovery in matrix was >86%, and the retention times were highly reproducible. The method was successfully applied to soil solution and fungal culture samples, demonstrating the advantages in successfully avoiding issues associated with high amounts of substances that may interfere with derivatization‐based methods. This method represents an alternative to derivatization‐based methods and can be applied in areas where sample matrices are highly complex.     

Controlled Release of Hepatocyte Growth Factor from MPEG‐b‐(PCL‐ran‐PLLA) Diblock Copolymer for Improved Vocal Fold Regeneration

An in situ‐forming gel system comprised of diblock copolymer formed from polyethylene glycol (PEG) and polycaprolactone (PCL) {MPEG‐b‐(PCL‐ran‐PLLA)} could be used in controlled drug delivery for tissue remodeling. The purpose of this study is to demonstrate favorable vocal folds (VF) regeneration by using MPEG‐b‐(PCL‐ran‐PLLA) diblock copolymers (C97L3; CL/LA ratio 97:3) incorporating hepatocyte growth factor (HGF). Gradual release of HGF from C97L3 is detected and biochemical properties of released HGF are maintained. A scar is made with microscissors on both VFs in 32 rabbits, followed by injection of HGF‐only, C97L3‐only, or HGF‐C97L3 composite gel in the left side VF, while the right side VF is left untreated. In vivo fluorescence live imaging system demonstrates that C97L3 enables the sustained release of injected HGF in the scarred VF for 12 weeks. The histological analysis shows increased glycosaminoglycan including hyaluronic acid accumulation and decreased collagen deposition. Videokymographic analysis shows more favorable vibrations of HGF‐C97L3 treated VF mucosa, compared to other treatment groups. In conclusion, the controlled HGF release helps to regulate extracellular matrix synthesis, and leads to the eventual functional improvement of the scarred VF.

     

Microparticle‐Mediated Delivery of BMP4 for Generation of Meiosis‐Competent Germ Cells from Embryonic Stem Cells

Producing meiosis‐competent germ cells (GCs) from embryonic stem cells (ESCs) is essential for developing advanced therapies for infertility. Here, a novel approach is presented for generation of GCs from ESCs. In this regard, microparticles (MPs) have been developed from alginate sulfate loaded with bone morphogenetic protein 4 (BMP4). The results here show that BMP4 release from alginate sulfate MPs is significantly retarded by the sulfated groups compared to neat alginate. Then, BMP4‐laden MPs are incorporated within the aggregates during differentiation of GCs from ESCs. It is observed that BMP4‐laden MPs increase GC differentiation from ESCs at least twofold compared to the conventional soluble delivery method. Interestingly, following meiosis induction, Dazl , an intrinsic factor that enables GCs to enter meiosis, and two essential meiosis genes (Stra8 and Smc1b ) are upregulated significantly in MP‐induced aggregates compared to aggregates, which are formed by the conventional method. Together, these data show that controlled delivery of BMP4 during ESC differentiation into GC establish meiosis‐competent GCs which can serve as an attractive GC source for reproductive medicine.

     

On the semicontinuity problem of fibers and global F-regularity

In this article, we discuss the semicontinuity problem of certain properties on fibers for a morphism of schemes. One aspect of this problem is local. Namely, we consider properties of schemes at the level of local rings, in which the main results are established by solving the lifting and localization problems for local rings. In particular, we obtain the localization theorems in the case of seminormal and F-rational rings, respectively. Another aspect of this problem is global, which is often related to the vanishing problem of certain higher direct image sheaves. As a test example, we consider the deformation of the global F-regularity.     

On maximal subalgebras and a generalized Jordan–Hölder theorem for Lie algebras

The purpose of this paper is to continue the study of chief factors of a Lie algebra and to prove a further strengthening of the Jordan–Hölder theorem for chief series.